Relationship between 25-Hydroxy Vitamin-D and Obesity in 2-7 years old Children Referred to a Paediatric Hospital in Iran
Published: September 1, 2014 | DOI: https://doi.org/10.7860/JCDR/2014/.4810
Sakineh Mohammadian, Reyhaneh Mortezazadeh, Hossein Zaeri, Mohammad Ali Vakili
1. Associate Professor, Golestan University of Medical Sciences, Taleghani Hospital, Gorgan, Iran.
2. Children Assistant, Golestan University of Medical Sciences, Taleghani Hospital, Gorgan, Iran.
3. Assistant Professor, Golestan University of Medical Sciences, Taleghani Hospital, Gorgan, Iran.
4. Assistant Professor, Golestan University of Medical Sciences, Taleghani Hospital, Gorgan, Iran.
Correspondence
Dr. Reyhaneh Mortezazadeh,
Golestan University of Medical Sciences, Taleghani Paediatrics Hospital, Janbazan Bolivar, Azadi Street, Gorgan, Golestan, Iran.
E-mail : reyhanehmortzazadeh@gmail.com
Background: Obesity is increasing in children and it can cause many complications in adulthood, such as Diabetes mellitus (DM) and metabolic syndrome. In observational studies, vitamin-D was one of the factors which were found to be associated with obesity.
Aims: To determine the association between body mass index (BMI) and serum level of vitamin-D in children who were outpatients at Taleghani Paediatric Hospital, Iran. Settings and Design: This was a cross-sectional observational study done on 215 children who were 2 to 7 y old, who were referred to Taleghani Hospital in winter (1391 solar calendar) 2013.
Materials and Methods: In this cross-sectional study, anthropometric indices: weight, height and waist circumference were measured by using identical instruments. BMI was also determined as per CDC 2000 criteria. Vitamin-D levels were estimated by ELISA.
Statistical Analysis: Vitamin-D levels which were less than 20 nmol/L were considered as a deficiency, levels which were 20-30 nmol\L were considered as inadequate and those which were equal to or greater than 30 nmol\L were considered as sufficient. t-test, ANOVA and Pearson’s correlation coefficient at a significant level of 0.05 were applied and data were analysed by using SPSS (version 16).
Results: One hundred and twenty five children (47.4%) were males and the rest were females. One hundred eighty four children (85.6%) had vitamin-D deficiency and only 31 had adequate levels of vitamin-D. The prevalence of obesity and overweight were 27%, but considering the vitamin-D status, it was found to be insignificant. However, there was a linear relationship between waist circumference and serum vitamin-D (p<0.01). The means and standard deviations of serum vitamin-D levels in girls and boys were 22.76 ±11.62 and 23.46 ± 9.30 nmol/L and this difference was not significant. Vitamin-D levels found in the three ethnic groups of Fars, Turkmen and Sistani showed significant differences (p<0.002).
Conclusion: There was a high prevalence of vitamin-D deficiency in 2 to 7 year olds. There was no significant relationship between BMI and vitamin-D, but it was recorded in ethnic groups, and there was a correlation between waist circumference and vitamin-D levels. More exposure to sunlight and prescription of vitamin supplements were recommended.
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